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Friday, April 11, 2014

The research chemical 25I-NBOMe - all you need to know about it


Chemical names:
4-Iodo-2,5-dimethoxy-N-(2-methoxybenzyl) Phenethylamine
2-(4-Iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl) Methylethanamine

History of 25I-NBOMe
25I-NBOMe is a very new research chemical. It was developed in Berlin, Germany in 2003. The work was picked up by Dr. David E. Nichols at the Purdue University where he also made more NBOMe substances from various other 2C-X substances.

It was in 2010 when 25I-NBOMe hit the market of research chemicals for the first time, it was than available via online shops. The research chemical 25I-NBOMe was sometimes sold as pure chemical, but in most cases the dosages had been already prepared on blotter paper similar to LSD.

After 25I-NBOMe became available in the internet, it also quickly appeared on the street and the blotters containing 25I-NBOMe had been sold as LSD.
The NBOMe substances are derivates of the phenethylamines, in this case it is the derivate of 2C-I.

Dosage of 25I-NBOMe
The dosage of the research chemical 25I-NBOMe varies greatly, depending on the person and the experience the person has with psychedelics. But in general effects can be felt with around 200 µg of the pure research chemical 25I-NBOMe, while an average dosage is set between 500-1000 µg. However there are many reports where people also use up to 2000 µg of the substance as a single dosage. It is important is to start with a low dosage and then adjust it until you reach the desired effects.
How to use Research chemical 25I-NBOMe
Routes of Administration of 25I-NBOMe
25I-NBOMe can be sniffed, smoked or used through the mouth mucosa. In most cases the research chemical 25I-NBOMe is used through the mouth mucosa, as the pieces of blotter are placed under the tongue or on the gums. It is important the saliva is also kept in the mouth, because unlike LSD the research chemical 25I-NBOMe is not active through the digestive system.

Smoking 25I-NBOMe does not always work, it depends in which form the research chemical 25I-NBOMe is delivered in.

Sniffing the pure research chemical 25I-NBOMe is also often not the best choice, because the very low dosage consists of a barely visible amount and thus this method offers a great risk from taking too much.

Effects of 25I-NBOMe
25I-NBOMe is a research chemical with strong psychedelic effects, even if it is an analogue of the research chemical 2C-I, the effects are quite distinct from each other. Many reports indicate that 25I-NBOMe is much closer to the effects of LSD than the research chemicals of the 2C-X class or 2C-I. This is based on the intensity and strength of the effects, as it will lead to strong visuals with closed and open eyes, a change in overall body feelings and to an affected pattern of thinking.

It is also interesting to know, that the effects of the research chemical 25I-NBOMe can be enhanced through the usage of cannabis, herbal incense or cannabinoids. Smoking cannabis, herbal incense or cannabinoids strongly boost the visual effects of the research chemical 25I-NBOMe. Experienced users often utilize that to push the effects at the beginning of a 25I-NBOMe experience, but for first time users and inexperienced users of psychedelics, this can be very rough and therefore somewhat overwhelming. But of course it is also possible to smoke cannabis, cannabinoids or herbal incense during the 25I-NBOMe experience and also when the effects start to fade away. During the experience of 25I-NBOMe it will also boost the visual effects, but it is less likely to overwhelm the consumer when the peak is already reached. At the end of the experience with the research chemical 25I-NBOMe it can be used to bring back the visual effects and make the consumer lengthen the experience a little bit.

Experience Report of 25I-NBOMe
Gender: Male
Age: 30
Weight: 87 kg
Route of administration of 25I-NBOMe: Mouth mucosa, placed on gums
Dosage of 25I-NBOMe: 1 mg on 2 blotters, each with 500 µg

Time 00:00 - The 25I-NBOMe Blotter was placed on the gums, directly after brushing the teeth and cleaning the mouth. I wanted to ensure a clean mouth mucosa to ensure a proper uptake.

Time 00:01 - There is a somewhat bitter and chemical taste spreading in my mouth, but I just keep the blotter on the gums and the saliva in the mouth.

Time 00:15 - The amount of saliva is getting more and I find it somewhat difficult to not swallow it now. The bitter taste of the 25I-NBOMe blotter is gone now. But my saliva seems to be somewhat slimy and I have the feeling of a metallic taste in my mouth.

Time 00:25 - It seems like the first effects would show themselves, I was walking from the living room into the kitchen and realized I felt a bit like drunk. But just like after a bottle of beer or so. The 25I-NBOMe blotter was still on my gums and I managed to not swallow the saliva until now.

Time 00:45 - The effects from the 25I-NBOMe blotter are now beginning to show some stronger effects, I feel far more intoxicated now. When I walk around in the room it now definitely feels like I drunk a good amount of alcohol, my legs are a bit wobbly. But the other effects of the 25I-NBOMe blotter are very different from alcohol; the colors slightly enhanced and seemed brighter, yet there are no visuals. Besides the color enhancement, my sight was as affected like after smoking a joint with a large amount of cannabis or herbal incense.

25I-NBOMe is a derivate of phenetylamine
Time 01:00 - I now took out the 25I-NBOMe blotter and finally swallowed the saliva. The effects are quite the same as 15 minutes earlier, but the color brightening has increased far more now, yet there are now visuals. I try to look around and check things I normally look at when I use psychedelics, everyone has something like a picture or lamp where you measure your status through the visuals. But no real changes yet. Thinking also remained normal until now, no funny psychedelic thinking yet.

Time 01:30 - Waiting for the full effects of the 25I-NBOMe is somewhat annoying, so I turned on the TV and put on the movie "Fear and Loathing in Las Vegas". A great movie for the beginning of the trip. I did not exactly realize when the 25I-NBOMe effects got more intense, but I realized my slowly changing pattern of thinking. I checked my status through looking at a picture on the wall. It now seemed to be coming out of the wall. So yes, the visuals of 25I-NBOMe had finally started.

Time 02:00 - This was around the moment where the 25I-NBOMe blotter reached its peak effects, everything I heard was sounding a bit numb and had some sort of echoes. Colors where mixing into each other and everywhere I looked at, patterns where occurring, changing, twisting and turning smoothly and slowly. Everything seemed to have several layers.

Time 03:00 - I was busy watching the visuals of the 25I-NBOMe, until then suddenly the movie was over and I felt the desire to hear music. Interestingly I was so busy with watching the visuals, that I had not thought about much nor followed the movie. The music was rather intense, the beat of it had a strong influence on the visuals; it somehow seemed the visual effects were like a visualizer. When I closed my eyes I was flying through colored tunnels with colorful patterns, the patterns in the tunnels where also moving to the beat of the music.

Time 05:00 - Again I was busy with all the visual effects from the 25I-NBOMe, no matter if with closed or open eyes. I just enjoyed the show. But since I was on 25I-NBOMe for a couple of hours now, I went outside. It was dark already and not much people where walking on the streets. I walked into a park the light bulbs somehow had a heart shape, a strong blue glow and with every step the world seemed to change. I decided not walk too far away from home, in case things would become too intense I could quickly get back.

Time 06:00 - Back at home I realized the effects had slightly lost intensity. I verified that by taking a look at the picture on the wall in the living room. I was a bit clueless what to do now so I turned on the TV again. I realized I could now think more normal again and the mixing of colors and pattering was losing intensity.

Time  08:00 - I still had slight visuals, but could think completely normal again. I decided to push the effects from the 25I-NBOMe blotter again through smoking a bong with herbal incense. It made a "woosh" and I had rather similar visuals again as during the peak, but the other aspects like thinking or changed perception of sound did not come back again.

Time 10:00 - I enjoyed the rest of the trip, but the visuals and all other effects faded with the effects of the herbal incense. I felt a little bit exhausted, but still somewhat stimulated and not able to sleep.

Time 12:00 Finally the stimulation was also gone and I was able to go to bed. I quickly fell into sleep.

I woke up after 8 hours of sleep and still felt a bit less energized than normal, but besides that I didn't feel hangover or having other after effects from the 25I-NBOMe blotter.

Thursday, March 27, 2014

The history and future of legal highs and research chemicals

Like you already realized from our previous explanation of what research chemicals are, the topic is rather difficult. Also the use of the term ‘research chemicals’ is new to the context of regular drugs and the name indicates a very broad term for chemicals for research. That could mean nearly every substance we know about could be a research chemical.

MDMA, 2C-B, 2C-C and other designer drugs in often are sold as pills
 The early days of research chemicals - the 1970s and 1980s

The first appearance of the research chemicals was during the 70s and 80s, when blotter containing DOM was sold as LSD blotter. This went on into the early 80s, when MDMA gained a large popularity and a wider audience, more and related substances occurred on the market as well. Of course in the 80s even MDMA could have been rated as research chemical, but besides MDMA there was also MDEA and some others going into the scene.

The raise of research chemicals and legal highs during the 1990s

But the real market for research chemicals was opened in the 90s, when the books from Alexander Shulgin started to spread around the world. Since 2C-B was rated from Alexander Shulgin as his best psychedelic under all the research chemicals he had made, it was clear that this would be the one to hit the market at first. A company called "Drittewelle" started to make pills which contained 5 mg 2C-B each and sold them as aphrodisiac. The name of the product was "Nexus". This was possibly the first biggest exposure of research chemicals to the public. The internet was just a small and unimportant technological mumbo jumbo in these days and thus neither the knowledge nor the pure research chemicals had been available.

Also the authorities had not been very aware of these research chemicals during the early stages, thus the research chemicals remained legal for a rather long time. After the ban of 2C-B, the marketing of pure research chemicals slowly begun to grow, but since Alexander Shulgin was one of the very few researchers who made their findings public, the research chemicals available had been mainly substances described in Shulgins books;TiHKAL and PiHKAL. The place from the research chemical 2C-B was quickly taken by TMA-2, 2C-T-2 and 2C-T-2. The legal highs, which make the biggest part of the research chemicals market today, were only a very small and unimportant niche during the late 1990s.

The legal highs market slowly becomes big in the 2000s

Since psychedelics are no research drugs for daily usage nor likely to be sold in large amounts, the market of research chemicals required something bigger to expand and become important. But the raise of further research chemicals from the book PiHKAL slowly made politics aware of these research drugs. The next step had been research chemicals with stimulant effects.

Ethylphenidate a popular legal high - march 2014
Some of the very first research chemicals with stimulant properties had been the cathinones; one of the most popular substances was Methylone, the cathinone derivate of MDMA. It shared many similarities in effects, but was a bit less potent and the overall effects are less intense. But slowly the market for research chemicals wasn't bound anymore to the substances described in Shulgin’s books. Through the internet many research papers become available to everyone and thus the chemical groups of research chemicals available on the market started to expand, leading to increased methods of attaining a legal high.  

This continued for several years, but still the marketed research chemicals mainly consisted of psychedelics, stimulants and euphoric stimulants such as Methylone. In the late 2000s the research chemicals market slowly begun to explode, a new product which later should be sold in millions per month raised on the market. But it also introduced a new group of research chemicals and introduced the big era of legal highs and research chemicals. The product was called Spice, a synthetic weed. Nearly everyone has heard of it at least once.

The synthetic cannabinoid Spice was the first product to contain cannabinoids from the group of research chemicals, it also was the first legal high introduced on the market that was a legal replacement for Cannabis. Since Cannabis is the illicit drug which is consumed globally by the largest group of people, a legal replacement for it was far more requested than a legal replacement for speed, LSD or XTC. So far the most remarkable legal highs had been from the research chemical Explosion which was an alternative to XTC, based on Methylone and sold as legal XTC.

Legal Highs and Research Chemicals in the 2010s

The synthetic weed Spice made nearly everyone aware of the existence of research chemicals and legal highs. But unlike the research on stimulants and psychedelics, the research chemicals of the cannabinoid class still remained rare in the public. It took a few years before a wide range of synthetic cannabinoids became available on the market as research chemicals.

But through the raise of the new legal highs with cannabinoids, the people also became more aware of legal highs in general. This opened the doors for more research chemicals to become big. One of them was the stimulant with euphoric properties known as Mephedrone, in the UK Mephedrone quickly became so big, that the dosages used per month where only beaten by legal drugs like alcohol and the only illicit drug sold more often than Mephedrone was Cannabis.

Many governments reacted by banning many substances with which to attain legal highs and by trying to keep track of all research chemicals that emerged the market. Some countries even began to make drug analogue laws, similar to the laws in the USA. These analogue laws make it possible to ban a research chemical and all other research chemicals that are similar in their chemical structure.

However even the analogue laws could not stop the increase in the market of more legal highs substances and research chemicals. Even if a whole group of chemical substances is banned by an analogue law, there are still enough chemical groups which are too distinct from the banned ones and thus remain legal drugs. These new replacements for the banned research chemicals trigger the same effects hence getting high legally. According to the European monitoring centre for drugs, research chemicals and legal highs, the amount of available research chemicals in Europe had previously been around 30-40 substances per year, but in 2012 that number climbed up to 70-80 research chemicals per year.

Mixing of research chemicals has created new designer drugs
This number of substances for legal highs is growing every year, because also more scientists have become aware of these research chemicals and thus new groups of research chemicals are added every couple years. One of the latest examples are NBOMe substances such as 25I-NBOMe. Nearly all substances described in Shulgin’s book ‘PiHKAL’ (standing for ‘’Phenethylamines I Have Known and Loved" ) can be made into a NBOMe version such as for example; 25D-NBOMe, 25H-NBOMe, 25I-NBOMe to name just a few. Potentially hundreds of possible new research chemicals and molecular structures can be created through just one single step.

Another factor is that research chemicals now cover nearly every group of drugs; stimulants, psychedelics, dissociatives, benzodiazepines and even opioids had been brought on the market.

The future of research chemicals and legal highs

After the Spice ban and the further bans of synthetic cannabinoids, many people believed the ban would cover the "best" synthetic legal weed categories of these research chemicals. But every time a ban emerged, a new range of legal synthetic cannabinoids had been brought on the market and even those who believed the cannabinoids with the best effects would have been gone, quickly realized how wrong they had been. After the first wave of bans on synthetic cannabinoids from the research chemicals, it took only a few months to find proper replacements and this will also continue in the future.

Some illicit drugs have unique effects so the amount of possible replacements through research chemicals seems to be initially limited. One example for this was LSD; there are only 2 known research chemicals which got the same effects and those are direct analogues of LSD, they are known as ETH-LAD and AL-LAD. But even if the chemical structure is different, the effects can be reproduced. That is the case with NBOMe substances such as 25I-NBOMe. They have a different chemical structure but are so potent and can create such intense effects, that many users confirm the mental and visual effects are quite similar to those of LSD.

It could happen that more countries start to try fighting research chemicals and legal highs through analogue laws. But the pressure on the political climate is still growing, because also analogue laws will not solve the situation. Some countries are already beginning to start review their laws and opinions of drugs in general. One thing is for sure, banning single drugs is not a solution anymore. Politicians finally have to face the reality that not everyone just wants to drink alcohol, take caffeine or smoke nicotine.

One of the few groups within the field of research chemicals, which don't have a large amount of replacements yet, are the opioids. But tendencies show that more and more people start to look for these alternatives. It is therefore likely that also the opioids will gain a huge boost in the research chemicals market during the next years.

On the other hand, for psychedelics the research chemicals market already has a lot of different substances to choose from and the number is growing permanently. This will also continue in the next years. The same will most likely take place with the research chemicals falling under the categories of stimulants, dissociatives and cannabinoids.

Laws against the use of drugs have always failed. In some countries the law already states it is illegal to consume any research chemicals in general, but if the research chemicals or legal highs are not sold for human consumption, they remain legal. And it is hard to proof the "abuse" of these research chemicals or legal highs if the costumer is behind closed doors in his own home. So even if there are efforts to stop research chemicals and legal highs, these efforts will fail as they always have before. Therefore if there is no legalization of certain currently illegal drugs, the research chemicals will remain as big as they are today. The more drugs are banned, the more legal alternatives and research chemicals appear to replace them to attain the same high but legally. Research chemicals categories will continue to grow until the politicians will be finally open to new ideas.

Since it could need decades to finally bring a change into the minds of politicians about research chemicals, legal highs and drugs, we can only estimate what are most likely the substances to come up next.

The stimulants are one of the most important classes within the research chemicals today, since amphetamines, cathinones and pyrovalerones are easy to produce and offer hundreds of possible analogues. Therefore the research chemicals within the stimulants will be most likely some of them. Even in the countries where analogue laws had been made, they do not cover all 3 types of these research chemicals in most cases.

For the psychedelics there will be also the same rules to follow for new research chemicals, the phenethylamines and amphetamines are in most cases easy to produce and do not require expensive equipment. The substances described and discovered by Alexander Shulgin such as 2C-B are already in the crosshair of authorities. However, they can't ban all of these research chemicals, except through analogue laws. But even then, there are many more groups for new research chemicals within the group of psychedelics. Especially the new appearance of the NBOMe substances such as 25i-NBOMe nearly worked around every analogue law. For this reason the coming years will especially see new psychedelics available which are from the NBOMe research chemicals and also with the previous stuff described by Shulgin.

But besides that there are also the tryptamines, in most cases these research chemicals are a bit more difficult to produce and cost more in production, therefore the companies will first try to make the cheaper research chemicals. But still there is already a wide range of legal tryptamines such as for example 5-MeO-DALT available and many more are emerging.

The synthetic cannabinoids group are for now the most unpredictable class of research chemicals, since they represent the biggest part of the market. But this also attracts a higher attention from all sides to these research chemicals. Therefore bans and analogue laws are likely to quickly ban whole groups of research chemicals within the synthetic cannabinoids group. This leads to the flourishing of a large number of research chemicals to become available, which are coming from totally different chemical groups but still are legal cannabinoids and used to attain legal highs. This makes it hard to say which research chemicals are more likely to appear the coming years. But one thing can be estimated, that every year will bring more and more different groups of synthetics cannabinoids on the market, just to have something legal in every country around the globe.

Thursday, December 26, 2013 Disclaimer and Information

This blog offers a large amount of knowledge about research chemicals, the history of these chemicals, the usage, the effects and much more. All information given is solely for personal purposes and interest. None of the information on this blog are intended to make people consume research chemicals, produce any psychoactive substances or to force criminal activities.

Best Research Chemicals is always looking to get you all information and keep you updated on new research, legality and more. But cannot guarantee 100% accuracy on the information published on the blog. We can never be hold responsible for any wrong information, not updated information or for abuse of the information given on our website.

In some countries the information available on this blog could considered illegal. We cannot keep track of the current status of research chemicals in every country worldwide. When you visit this blog you agree that you are allowed to see and read the material published on this blog and you agree to not abuse any information you found on this blog.

4-HO-MET synthetic psychedelic drug with similar effect to psilocin
Since it is hard to keep track on what is going on in the research drugs area all around the world, we try to pack all essential information into an easy to understand article. Some scientific knowledge is hard to understand and difficult to read for someone who is not familiar with the subject, therefore we try to explain them to make you understand it easier. You will find information about the history of research chemicals, latest research done on research chems, interesting facts about legal highs, 25I-NBOMe information, 2C-C information, 4-HO-MET information and much more.

If you want to be part of the research chemicals movement or you want to have an affiliation with this blog, please write a detailed email and send it to:

Important Note: No questions about the synthesis of research chemicals, their usage, effects or anything else, will be answered via email. You can post comments in the specific topics and thus make your question and the answer available to everyone.

Monday, September 9, 2013

What are Research Chemicals?

Research Chems & LSD The terminology of research chemicals is often misunderstood; many people have designer drugs in mind when they think of research chemicals. But designer drugs are specially designed chemicals by underground labs to avoid laws and have a completely unknown chemical in their stock. This is also happening from time to time, but the available legal highs contain less than 1% of designer drugs.

A common research chemical was always developed for research; this could be the pharmaceutical research, where companies look for new medications and substances they can use within their meds or to investigate specific reactions in the human body to gain more knowledge on how the human body works.

The best example for this would be LSD; Albert Hofmann was researching the alkaloids present in ergot. The primary goal was to find new substances that might help on problems with the circulatory system and also to be used as aid during the birth. LSD did not show the wanted effects in animal trials and so would have been nearly passed without noting its psychedelic effects. It was just an accident that Albert Hofmann found these effects and tested the substance on him to proof them. Even if LSD is not really rated as research chemical today, many of the modern research chemicals show strong similarities to the early history of LSD.

2C-C research chemical
Another part where research chemicals come from, are chemists who are looking for several ways what and how they could change a molecule, therefore they change as many parts as they can and each single change, no matter how minimal it is, is a new research chemical. A good example for doing this is Alexander Shulgin, he developed hundred of substances and noted all his findings in the books “Thikal and Phikal”. The interesting fact is that his research begun with Mescaline, he found the effects of mescaline so amazing, that he wanted to see if he could enhance its effects through small changes on the molecule. These research chemicals can be found in the book Phikal, most people have already heard about at least one of his findings; most popular are substances like 2C-B, 2C-C, 2C-E, 2C-T-7 and much more. All of them are similar in their chemical structure, often there is just one atom that had been changed.

The third part of research chemicals comes from a more closely related field of research, where scientific teams are looking to extract specific effects from an already existing and psychoactive substance. A good example for this is cocaine, which has strong local anesthetic effects, but through its strong stimulating, euphoric and addictive potential, it was not the best choice for the medical usage. Today we have many substances which are directly based upon the cocaine structure, but don't share any effects with cocaine except the anesthetic ones. One well known of these substances is Lidocaine, commonly used by the dentists.

But to find these desired chemicals, the research teams produced a large amount of different research chemicals. Of course some of them brought them closer to their goal, but still had psychoactive effects, an example is Dimethocaine. Dimethocaine has around 10-30% of the potency of cocaine, but around the same potency in numbing effects. But because there was no medicinal use for it, since Lidocaine and other substances worked better, Dimethocaine remained a research chemical in the research papers for decades.

Since Cocaine is illegal in almost every part of the world and still has a large amount of consumers, there was a market for the research chemical Dimethocaine as well. So Dimethocaine occurred again during the 2000s and the 2010s with many other research chems.

But research chemicals also cover all kinds of drugs and substance groups, so we want to give you a little insight in the 5 most important classes and what they are all about:

Cannabinoids are in general research chemicals which mimic the effects of natural cannabis or better said natural THC. But if you search around you might be confused, because the usage of the word cannabinoids for research chemicals isn't very accurate. This means if you read about cannabinoids in scientific papers you could come across cannabinoids and cannabimimetica in one sentence. The correct usage of the word cannabinoids only counts for the natural occurring substances within cannabis, such as THC, CBD and similar. But the research chemicals that are called cannabinoids are just substances which mimic the effects of these cannabinoids, it doesn't mean they have similar structure compared with THC and alike. The correct terminology for these research drugs would be cannabimimetica, as they are only acting at the same receptors as natural cannabinoids and thus creating the same or similar effects.

Since scientific papers need to be as accurate as possible, it is most likely you come across both words, cannabinoids and cannabimimetica for the research chemicals you want to learn about. Since you know now what is behind cannabinoids, you will be able to understand what they are talking about. Most of the legal herbal incenses on the market have Cannabinoids on it.


Stimulants is a small word that has a large meaning, research chemicals with stimulating effects can come from a lot of different chemical groups and can work in many different ways. Some of the most important groups of stimulants within this group of research chems are the amphetamines and cathinones, but even these two are very closely related to each other. Most if not all amphetamines can be also made as cathinones and vise versa. Both groups of research chemicals are based upon the structure of ß-Phenethylamines, but this structure is also the base for many psychedelic drugs which have no or little stimulating effects. But before things are getting too complicated, we try to explain it step by step.

Cathinone is a naturally occurring substance from the plant Khat, amphetamine is only available as chemical and cannot be found naturally. Still the difference is just a single oxygen atom at a specific part of the structure, without that oxygen atom the substance is an amphetamine, with the oxygen atom it is a cathinone. Cathinones are commonly a bit weaker than their amphetamine cousins, but while some amphetamines are toxic, the somewhat lower potency of the cathinone version can make it a less toxic and pleasurable drug. One of the most remarkable and popular research chemical from the cathinone class in the past few years was Mephedrone also known as 4-MMC and Methylone the cathinone version of MDMA.

The same rule applies for methamphetamines, where the cousins are the methcathinones. But any change on the structure of both research chemical groups can have a strong influence on the intensity, potency and duration, but also on the overall effects. Depending on the position of the attachment on the molecule, the stimulants might become more intoxicating, euphoric or similar. A good comparison is MDMA to Methamphetamine, one is a strong euphoric intoxicant with medium stimulant effects, while the other one is a very potent stimulant.

Through the large amount of options to change the structure of amphetamines and cathinones, there are hundreds of possible research chemicals with psychoactive effects. Only a few of them are banned by laws, this makes them a perfect choice to continue fighting against the war on drugs.

There are also several more substance groups of the stimulants; one of them is the one where the substance Methylphenidate comes from, which is commonly used in the medicine Ritalin. Through the addition of a further carbon atom, you get the research chemical Ethylphenidate, it has similar effects as Methylphenidate but is slightly more euphoric and has a little shorter duration.

Another group of stimulants from the research chemicals are the so called pyrovalerones, these are also structurally related to amphetamines and cathinones, but often only share a part of the effects. The most popular research chemical of the pyrovalerones is for sure MDPV, it is the pyrovalerone version of MDMA, but it doesn't produce the same music appreciation of MDMA and also the feeling of being intoxicated is less pronounced. This means the pyrovalerones regular are not in the same line as the amphetamines and cathinones.


Like the research chemicals group of stimulants, the psychedelics also cover a wide range of different chemical groups and classes. The two most important groups of psychedelics are the ß-Phenethylamines and Tryptamines. Some of the most popular representatives of the ß-Phenethylamines are Mescaline, 2C-B, 2C-D, DOM and 2C-T-7, while some of the most important substances from the Tryptamines are LSD, DMT and Psilocin/Psilocybin.

Many popular drugs and also research chemicals from both groups are banned already, but since Alexander Shulgin is developing more and more research chemicals from both groups, there is an endless number of research chemicals to quickly replace the banned ones. Similar to the situation with the stimulants, nearly every psychedelic from the group of ß-Phenethylamines can be made in two different versions, the phenethylamine research chemicals and the amphetamine cousin of it. Usually the amphetamine versions of the phenethylamine psychedelics are more potent, create longer lasting effects and are more intense. Often they share similar effects, but in some cases the research chemicals from the amphetamine class are distinct in effects from their phenethylamine cousins.

Research drug 2C-I-NBOMe
During the year 2003 there was a further addition to the research chemicals of the ß-Phenethylamine group, the so called NBOMe substances. This made it also possible to make nearly any psychedelic research chemical available as phenethylamine, amphetamine and also as NBOMe. An example for this is the phenethylamine 2C-I, where the amphetamine version is known as DOI and the NBOMe version is known as 25I-NBOMe. Each step made the substance more potent, the research chemical 2C-I requires tenth of milligrams to develop its effects, while DOI only needs a few milligrams and 25I-NBOMe is in the sub milligram area.

The Tryptamines do not offer the same large amount of possible analogues, so the amount of research chemicals and especially psychedelics are lower. But that doesn't make them less interesting, did you know you can legally consume LSD as long as you do not live in a country with analogue laws?

Yes you read right, there are research chemicals which are based on LSD and are just different in a few atoms, the effects are very similar, experience reports claim the same effects, duration and intensity of the experiences. The only difference between LSD and the research chemicals AL-LAD and ETH-LAD is the dosage, the two newer analogues are said to be more potent than LSD.

AL-LAD analogue of LSD
But most laws only list LSD as illegal drug and not its direct analogues AL-LAD and ETH-LAD, thus they are both legal in most countries.

But there are more interesting psychedelics in the area of Tryptamines, one further example is 4-AcO-DMT, it is directly converted into Psilocin in the human body. Therefore it is exactly like using magic mushrooms, but since the structure of this research chemical is slightly different, it is also legal in most countries. But even if 4-AcO-DMT is banned, there is also 4-HO-MET and many other which are also known to produce very similar if not the same effects as magic mushrooms.


The dissociatives also cover several chemical classes, but the amount of research chemicals from the group of dissociatives are not as big as the other ones. One reason for this is the kind of effects they produce, not as much people are looking for research drugs that produce dissociative effects.

Some of the most popular drugs from the group of dissociatives are PCP also known as Angle Dust and Ketamine. Like with any research chemicals mentioned before, these chemicals can also be changed with single atoms and thus creating a new substance. Currently the most important one is Methoxetamine, an analogue of the popular drug Ketamine, it is often just called MXE.


The most benzodiazepines are no research chemicals, they are commonly prescribed medicine against spasm, for muscle relaxation, to promote or enhance sleep and also to treat fear and panic attacks. But still there are a few substances which never hit the market and therefore remain as research chemicals or they had not been used in every part of the world and are therefore not listed in the law.

Popular research chemicals of this group are Phenazepam and Etizolam. Phenazepam is currently available especially in Europe and the USA as research chemical, but the truth is, it is a common pharmaceutical from Russia. It was developed during the cold war and was made to avoid a dependency from the western civilizations, it is still often used in Russia and the countries at the Russian border. Etizolam shares a similar history and how it found its way into the market of research chemicals.

Tuesday, September 3, 2013

Best Research Chemicals Blog

Welcome to our new blog about Research Chemicals (they are also commonly called research drugs)! Here you can find all the information you need about herbal incenses and new research chems on the market. We also provide information about the usage and dosage of the best research chemicals you can possibly imagine, including: 2c-c, 25i-nbome, 5-meo-dalt, 4-ho-met and much more!